We’ve added four new videos to our Coronavirus Pandemic (COVID-19) Updates Explained Clearly course on MedCram.com, covering diabetes and COVID-19, re-infections, immunity, academic censorship, and more. Check out our full scope of COVID-19 updates and information here.
Dentists; Diabetes; Sensitivity of COVID-19 Antibody Tests
In our 72nd COVID-19 update, Dr. Seheult looks at case numbers around the world and in the U.S., as we start to see some public spaces reopening for business. In addition, he discusses the sensitivity and specificity of antibody testing, citing this study, which looked at four different commercially available tests.
Dr. Seheult also discusses the interaction between diabetes and COVID -19, drawing from this study the role that glycosylated hemoglobin (HbA1c) may play in determining the hypercoagulability and prognosis for coronavirus patients. Lastly, Dr. Seheult mentions the challenges faced by dentists regarding a lack of clear guidelines and expectations for reopening and providing oral healthcare.
Relapse, Re-Infections, & Re-Positives – The Likely Explanation
In the 73rd MedCram COVID-19 update, Dr. Seheult talks about people re-testing positive for COVID-19 even after their symptoms have dissipated. In doing so, he illustrates the mechanisms of Reverse Transcriptase Polymerase Chain Reaction, or RT-PCR, testing. These tests, which rely on sampling RNA, could potentially pick up a fragment of RNA from viral particles already decimated by the immune system — which can no longer infect the host and cause COVID-19. Further, Dr. Seheult looks at a press release from the Korean CDC on re-infection and re-positives of COVID-19. This research supports the idea that positive tests for patients who have already recovered from COVID-19 may actually be picking up remnants of viral RNA strands, which are incapable of reinfecting the host and infecting others in close contact.
Vitamin D & COVID-19; Academic Censorship
In our 74th COVID-19 video update, Dr. Seheult briefly revisits the conversation on dentists and provides links to resources with information on reopening dental offices. He also discusses this article from The Lancet, which compares mortality rates among countries and looks at the potential role of Vitamin D in COVID-19. As such, he points out the censorship and dilution of the nuance of such information — such as YouTube’s removal of any videos that are not aligned with WHO recommendations — which effectively limits academic discussion of emerging information from peer-reviewed journals or pre-print publications about potentially important supplements and practices that better equip one’s immune system to deal with COVID-19.
COVID-19 Lung Autopsies – New Data
In our 75th coronavirus pandemic update, Dr. Seheult talks about the realities of starting to reopen public spaces in San Bernardino County, California, where he works. He also revisits the hypothesis we’ve been talking about for the past few weeks: that SARS-CoV-2 is, to a large extent, a disease of the endothelium. This Washington Post article reports on the New England Journal of Medicine article mentioned below that supports this hypothesis..
The article from the New England Journal of Medicine found that the lungs of patients who died from COVID-19 had “severe endothelial injury associated with the presence of intracellular virus and disrupted cell membranes” and widespread thrombosis, which differentiates SARS-CoV- 2 from the influenza virus. Another article from Science discusses the response of the adaptive immune system and T cells in COVID-19 — and how T cells primed to attack SARS-CoV-2 may already be present in some individuals who haven’t had COVID-19.
Stay Tuned for More COVID-19 Updates
As always, find all of our COVID-19 videos for free (and ad-free) at MedCram.com. While you’re there, check out our full library of courses and lectures on other subjects ranging from Asthma Explained Clearly to Urinalysis Explained Clearly and many more!
Meanwhile, here’s a list of all the COVID-19 resources we’ve shared so far:
- Coronavirus Outbreak, Transmission, and Pathophysiology
- Coronavirus Symptoms, Diagnosis, and Treatment
- Coronavirus Update 3: Spread, Quarantine, Projections, and Vaccine
- How Coronavirus Kills: Acute Respiratory Distress Syndrome (ARDS) & Treatment
- Coronavirus Epidemic Update 5: Mortality Rate vs SARS / Influenza
- Coronavirus Outbreak Update 6: Asymptomatic Transmission & Incubation Period
- Coronavirus Epidemic Update 7: Global Health Emergency Declared, Viral Shedding
- Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine, & MRSA
- Coronavirus Epidemic Update 9: Fecal-Oral Transmission, Recovery vs Death Rate
- Coronavirus Epidemic Update 10: New Studies, Transmission, Spread from Wuhan, Prevention (nocv 2019)
- Coronavirus Epidemic Update 11: Antiviral Drugs, Treatment Trials for nCoV (Remdesivir, Chloroquine)
- Coronavirus Epidemic Update 12: Unsupported Theories, Pneumonia, ACE2 & nCoV
- Garage Talk Podcast — Dr. Roger Seheult and the Coronavirus
- Coronavirus Epidemic Update 13: Li Wenliang, nCoV vs Influenza, Dip in Daily Cases, Spread to Canada
- Forbes Article – Medical Experts Employ Social Media To Battle Coronavirus
- Coronavirus Epidemic Update 14: Hospital spread of infection, WHO allowed in China, N-95 masks
- Coronavirus Epidemic Update 15: Underreporting, Prevention, 24 Day Incubation? (COVID19)
- Coronavirus Epidemic Update 16: Strengthening Your Immune Response to Viral Infections (COVID-19)
- Coronavirus Epidemic Update 17: Spike in Confirmed Cases, Fighting Infections with Sleep (COVID-19)
- Coronavirus Epidemic Update 18: Cellphone Tracking, Increase in Hospitalizations, More Sleep Tips
- Coronavirus Epidemic Update 19: Treatment and Medication Clinical Trials
- Coronavirus Epidemic Update 20: Misinformation Spread, Infection Severity, Cruise Ship, Origins
- Coronavirus Epidemic Update 21: Antibodies, Case Fatality, Clinical Recommendations, 2nd Infections?
- Coronavirus Epidemic Update 22: Spread Without Symptoms, Cruise Quarantine, Asymptomatic Testing
- Coronavirus Epidemic Update 23: Infections in Kids & Pregnancy, South Korea, Spillover From Bats
- Coronavirus Epidemic Update 24: Infections in Italy, Transmissibility, COVID-19 Symptoms
- Coronavirus Epidemic Update 25: Vaccine Developments, Italy’s Response, and Mortality Rate Trends
- How Viruses Work – Molecular Biology Simplified (DNA, RNA, Protein Synthesis)
- Coronavirus Epidemic Update 26: Treatment Updates, Stock Markets, Germany & San Francisco, Pandemic?
- Coronavirus Epidemic Update 27: Testing accuracy for COVID-19 (CT Scan vs. RT-PCR), California Cases
- Coronavirus Epidemic Update 28: Practical Prevention Strategies, Patient Age vs. Case Fatality Rate
- Coronavirus Epidemic Update 29: Testing problems, mutations, COVID-19 in Washington & Iran
- Coronavirus Epidemic Update 30: More Global COVID-19 Outbreaks, Vitamin D May Aid Prevention
- Coronavirus Epidemic Update 31: Mortality Rate, Cleaning Products, A More/Less Severe Virus Strain?
- Coronavirus Epidemic Update 32: Important Data from South Korea, Can Zinc Help Prevent COVID-19?
- Coronavirus Epidemic Update 33: COVID-19 Medication Treatment Trials, Global Testing Remains Limited
- Coronavirus Epidemic Update 34: US Cases Surge, Chloroquine & Zinc Treatment Combo, Italy Lockdown
- Coronavirus Pandemic Update 35: New Outbreaks & Travel Restrictions, Possible COVID-19 Treatments
- Coronavirus Pandemic Update 36: Flatten The COVID-19 Curve, Social Distancing, Hospital Capacities
- Coronavirus Pandemic Update 37: The ACE-2 Receptor – The Doorway to COVID-19 (ACE Inhibitors & ARBs)
- Coronavirus Pandemic Update 38: How Hospitals & Clinics Can Prepare for COVID-19, Global Cases Surge
- Coronavirus Pandemic Update 39: Rapid COVID-19 Spread with Mild or No Symptoms, More on Treatment
- Coronavirus Pandemic Update 40: Ibuprofen and COVID-19 (are NSAIDs safe?), Trials of HIV medications
- Coronavirus Pandemic Update 41: Shelter In Place, FDA Investigates Hydroxychloroquine for COVID-19
- COVID-19 Ventilator Course: Learn or Review Mechanical Ventilation (Free at MedCram.com)
- Coronavirus Pandemic Update 42: Immunity to COVID-19 and is Reinfection Possible?
- Coronavirus Pandemic Update 43: Shortages, Immunity, & Can a TB Vaccine (BCG) Help Prevent COVID-19?
- Coronavirus Pandemic Update 44: Loss of Smell & Conjunctivitis in COVID-19, Is Fever Helpful?
- Coronavirus Pandemic Update 45: Sharing Ventilators, More on Sleep, Immunity, & COVID-19 Prevention
- Coronavirus Pandemic Update 46: Can Hot/Cold Therapy Boost Immunity? More on Hydroxychloroquine
- Coronavirus Pandemic Update 47: Searching for Immunity Boosters & Possible Lessons From Spanish Flu
- Coronavirus Pandemic Update 48: Curve Flattening in California, PPE in the ICU, Medication Trials
- Coronavirus Pandemic Update 49: New Data on COVID-19 vs Other Viral Infections (Ventilator Outcomes)
- Coronavirus Pandemic Update 50: Dip in Daily New Deaths; Research on Natural Killer Cells & COVID-19
- Coronavirus Pandemic Update 51: State by State Projections; Ultrasound to Diagnose COVID19 Pneumonia
- Lung Ultrasound in COVID 19: Findings, Accuracy, Pneumonia Diagnosis, Utility (POCUS)
- Coronavirus Pandemic Update 52: Ivermectin Treatment; Does COVID-19 Attack Hemoglobin?
- Coronavirus Pandemic Update 53: Anticoagulation; Can Mechanical Ventilation Make COVID 19 Worse?
- Coronavirus Pandemic Update 54: COVID-19 Antibody vs. PCR Testing; When to Relax Social Distancing?
- Coronavirus Pandemic Update 55: How COVID-19 Infection Attacks The Immune System & Differs From HIV
- Coronavirus Pandemic Update 56: What is “Forest Bathing” & Can It Boost Immunity Against Viruses?
- Coronavirus Pandemic Update 57: Remdesivir Treatment Update and Can Far-UVC Disinfect Public Spaces?
- Coronavirus Pandemic Update 58: Testing; Causes of Hypoxemia in COVID-19 (V/Q vs Shunt vs Diffusion)
- Coronavirus Pandemic Update 59: Dr. Seheult’s Daily Regimen (Vitamin D, C, Zinc, Quercetin, NAC)
- Coronavirus Pandemic Update 60: Hydroxychloroquine Update; NYC Data; How Widespread is COVID-19?
- Coronavirus Pandemic Update 61: Blood Clots & Strokes in COVID-19; ACE-2 Receptor; Oxidative Stress
- Coronavirus Pandemic Update 62: Treatment with Famotidine (Pepcid)?
- Coronavirus Pandemic Update 63: Is COVID-19 a Disease of the Endothelium (Blood Vessels and Clots)?
- Coronavirus Pandemic Update 64: Remdesivir COVID-19 Treatment Update
- COVID-19 Clinical Updates & Lessons Learned So Far with Dr. Seheult – Live Webcast Replay
- Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Prevention & Risk Factors)
- Coronavirus Pandemic Update 66: ACE-Inhibitors and ARBs – Hypertension Medications with COVID-19
- Coronavirus Pandemic Update 67: COVID-19 Blood Clots – Race, Blood Types, & Von Willebrand Factor
- Coronavirus Pandemic Update 68: Kawasaki Disease; Minority Groups & COVID-19
- Coronavirus Pandemic Update 69: “NAC” Supplementation and COVID-19 (N-Acetylcysteine)
- Coronavirus Pandemic Update 70: Glutathione Deficiency, Oxidative Stress, and COVID 19
- Coronavirus Pandemic Update 71: New Data on Adding Zinc to Hydroxychloroquine + Azithromycin
- Coronavirus Pandemic Update 72: Dentists; Diabetes; Sensitivity of COVID-19 Antibody Tests
- Coronavirus Pandemic Update 73: Relapse, Reinfections, & Re-Positives – The Likely Explanation
- Coronavirus Pandemic Update 74: Vitamin D & COVID 19; Academic Censorship
- Coronavirus Pandemic Update 75: COVID-19 Lung Autopsies – New Data