{"id":1305,"date":"2022-08-17T10:39:02","date_gmt":"2022-08-17T17:39:02","guid":{"rendered":"https:\/\/blog.medcram.com\/?p=1305"},"modified":"2022-08-24T10:51:31","modified_gmt":"2022-08-24T17:51:31","slug":"near-infrared-light-can-reduce-inflammation-sars-cov-2-virus","status":"publish","type":"post","link":"https:\/\/blog.medcram.com\/covid-19\/near-infrared-light-can-reduce-inflammation-sars-cov-2-virus\/","title":{"rendered":"Near Infrared Light Reduces Inflammation via TLR4 In Vitro"},"content":{"rendered":"<p style=\"text-align: center;\"><iframe loading=\"lazy\" title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/e6xj14QYsoc\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p><span style=\"font-weight: 400;\">In this video, Dr. Seheult of MedCram discusses how near infrared light can reduce inflammation in a pathway that is used by the SARS-CoV-2 virus.\u00a0 He discusses an <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8451450\/pdf\/KCIB_14_1965718.pdf\"><span style=\"font-weight: 400;\">article<\/span><\/a><span style=\"font-weight: 400;\"> that analyzes how infrared light may reduce theTLR-4 dependent inflammatory response pathway and perhaps mitigate the cytokine response that is evoked by the innate immune system.<\/span><\/p>\n<h2>Can sunlight neutralize the spike protein on SARS-CoV-2?<\/h2>\n<p><span style=\"font-weight: 400;\">The question is, could sunlight actually neutralize a component of the SARS-CoV-2 virus, the spike protein? MedCram recently did a <\/span><a href=\"https:\/\/youtu.be\/NgiU8q_xf3g\"><span style=\"font-weight: 400;\">video<\/span><\/a><span style=\"font-weight: 400;\"> discussing how the TLR-4 receptors were implicated in the inflammatory response seen in cardiac cells.\u00a0 It was felt that the TLR-4 receptor protein, which is found on the surface of cells, was the nitus for attracting natural killer cells and instigating an inflammatory response that was independent of the ACE2 receptor.\u00a0<\/span><\/p>\n<h2>Infrared light<\/h2>\n<p><span style=\"font-weight: 400;\">It is exciting news that there may be something that could ramp down the TLR-4 dependent inflammatory response pathway. MedCram has discussed the usage of light previously to help with medical issues in this<\/span><a href=\"https:\/\/www.youtube.com\/watch?v=5YV_iKnzDRg\"><span style=\"font-weight: 400;\"> video<\/span><\/a><span style=\"font-weight: 400;\">. This current MedCram video discusses how near infrared radiation actually puts the brakes on the inflammation created by the TLR-4 receptors.\u00a0 Infrared light makes up the bulk of the energy coming from the sun. It is a low frequency energy that can penetrate into the skin and into the subcutaneous tissue and can be perceived as heat. Some articles have shown that it can penetrate up to 8 cm deep into the body. In fact, even with the brain, sunlight can penetrate the bone and stimulate the gray matter of the\u00a0 brain.\u00a0 Outdoors, the leaves and trees can reflect the infrared light.<\/span><\/p>\n<h2>TLR-4 receptor pathway<\/h2>\n<p><span style=\"font-weight: 400;\">This <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8451450\/pdf\/KCIB_14_1965718.pdf\"><span style=\"font-weight: 400;\">paper<\/span><\/a><span style=\"font-weight: 400;\"> tries to see if infrared light can block the mediation of the TLR-4 pathway.\u00a0 The scientists took HEK293 cells which use the TLR-4 pathway. LPS, a component of bacteria that can stimulate the innate immune system, was used to trigger the TLR-4 pathway. The prior <\/span><a href=\"https:\/\/www.dicardiology.com\/content\/coronavirus-spike-protein-activated-natural-immune-response-damaged-heart-muscle-cells\"><span style=\"font-weight: 400;\">paper<\/span><\/a><span style=\"font-weight: 400;\"> showed that the SARS-CoV-2 spike protein too can induce this pathway. When they gave near infrared light to the HEK293 cells, it was able to block the TLR-4 activation and prevent it from going to the nucleus and causing transcription of the inflammatory markers that will set off the inflammatory cascade. The authors are suggesting that perhaps in the future, COVID-19 patients, could have infrared light applied to their chest to see if there is any improvement as part of future research. <\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Benefit of sunlight<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There is evidence that getting sunlight and exposure to near infrared light may be of significant benefit with little negative side effects. A 100 years ago, people were getting more sunlight compared to today\u2019s society. Today people are spending less time outside overall. The windows we use in buildings now have become more efficient at blocking near infrared and the lights we use now have little to no infrared light associated with them. \u00a0 All of these changes have led to less exposure to infrared light.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It may be time to start looking at the benefits of getting outside and getting sunlight and how it may improve your health.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">LINKS \/ REFERENCES:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Infrared light therapy relieves TLR-4 dependent hyper-inflammation of the type induced by COVID-19 (Communicative &amp; Integrative Biology) |<\/span><a href=\"https:\/\/www.youtube.com\/redirect?event=video_description&amp;redir_token=QUFFLUhqbHAwWDJkN29abTU5aUlzcTZoTmVEYVVqSGJOUXxBQ3Jtc0ttS2FySmVCVzVyUE4tbl9lWmgzLTNMaFdHT1NyTjVzZEZuWjI4cmU0ZGlUMkRJcUZmTG00Y2tKS19xWG5QTmgwaG9jN1kzTU9nVUhkYnR6UXl1WUdkcDRzZEFuSmd5Y3U2OGFHNzRrVU1Ea2k1ZnlESQ&amp;q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC8451450%2Fpdf%2FKCIB_14_1965718.pdf&amp;v=e6xj14QYsoc\"> <span style=\"font-weight: 400;\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/arti&#8230;<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">The Case for Sunlight in COVID 19 Patients: Oxidative Stress (MedCram) |<\/span><a href=\"https:\/\/www.youtube.com\/watch?v=2Zzo4SJopcY&amp;t=0s\"> <span style=\"font-weight: 400;\">https:\/\/youtu.be\/2Zzo4SJopcY<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Sunlight: Optimize Health and Immunity (Light Therapy and Melatonin) (MedCram) |<\/span><a href=\"https:\/\/www.youtube.com\/watch?v=5YV_iKnzDRg&amp;t=0s\"> <span style=\"font-weight: 400;\">https:\/\/youtu.be\/5YV_iKnzDRg<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">SARS-CoV2 Spike Protein Expression in Mice Causes Damage via Innate Immune System (MedCram) |<\/span><a href=\"https:\/\/www.youtube.com\/watch?v=NgiU8q_xf3g&amp;t=0s\"> <span style=\"font-weight: 400;\">https:\/\/youtu.be\/NgiU8q_xf3g<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">All coronavirus updates are at <a href=\"https:\/\/www.medcram.com\/collections?category=covid-19-SARS-CoV-2\"> MedCram.com<\/a> (including more discussion on delta variant COVID, COVID Delta, COVID children, natural immunity COVID 19, and more).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">MedCram Update 46:<\/span><a href=\"https:\/\/www.youtube.com\/watch?v=EFRwnhfWXxo&amp;t=0s\"> <span style=\"font-weight: 400;\">https:\/\/youtu.be\/EFRwnhfWXxo<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">MedCram Update 47:<\/span><a href=\"https:\/\/www.youtube.com\/watch?v=H1LHgyfPPQ8&amp;t=0s\"> <span style=\"font-weight: 400;\">https:\/\/youtu.be\/H1LHgyfPPQ8<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">MedCram Update 132:<\/span><a href=\"https:\/\/www.youtube.com\/watch?v=9OZZ6_M4OB0&amp;t=0s\"> <span style=\"font-weight: 400;\">https:\/\/youtu.be\/9OZZ6_M4OB0<\/span><\/a><\/p>\n<h2><b>Stay Tuned for More Updates <\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Our COVID-19 videos are always available for <\/span><i><span style=\"font-weight: 400;\">free <\/span><\/i><span style=\"font-weight: 400;\">(and ad-free) at<\/span><a href=\"https:\/\/www.medcram.com\/collections?category=covid-19-SARS-CoV-2\"> <span style=\"font-weight: 400;\">MedCram.com<\/span><\/a><span style=\"font-weight: 400;\">. In addition, check out our full library of courses and lectures on subjects ranging from<\/span> <a href=\"https:\/\/www.medcram.com\/courses\/hypertension-explained-clearly-2\"><span style=\"font-weight: 400;\">Hypertension Explained Clearly<\/span><\/a><span style=\"font-weight: 400;\"> to<\/span><a href=\"https:\/\/www.medcram.com\/courses\/sleep-apnea-explained-clearly\"> <span style=\"font-weight: 400;\">Sleep Apnea Explained Clearly<\/span><\/a><span style=\"font-weight: 400;\"> Course and many more!<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Meanwhile, you can find all of our COVID-19 videos compiled <\/span><a href=\"https:\/\/www.medcram.com\/collections?category=covid-19-SARS-CoV-2\"><span style=\"font-weight: 400;\">here<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Visit <\/span><a href=\"https:\/\/www.medcram.com\/\"><span style=\"font-weight: 400;\">MedCram.com<\/span><\/a><span style=\"font-weight: 400;\"> for updates on Monkeypox virus infectious disease and more.<\/span><\/p>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>In this video, Dr. Seheult of MedCram discusses how near infrared light can reduce inflammation in a pathway that is used by the SARS-CoV-2 virus.\u00a0 He discusses an article that analyzes how infrared light may reduce theTLR-4 dependent inflammatory response pathway and perhaps mitigate the cytokine response that is evoked by the innate immune system.&hellip;<!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":8,"featured_media":1306,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.7 - 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