{"id":1361,"date":"2022-10-17T11:40:14","date_gmt":"2022-10-17T18:40:14","guid":{"rendered":"https:\/\/blog.medcram.com\/?p=1361"},"modified":"2022-10-25T12:02:07","modified_gmt":"2022-10-25T19:02:07","slug":"pfizer-vaccine-ability-prevent-transmission-sars-cov-2","status":"publish","type":"post","link":"https:\/\/blog.medcram.com\/covid-19\/pfizer-vaccine-ability-prevent-transmission-sars-cov-2\/","title":{"rendered":"Does the Pfizer Vaccine Stop Transmission?"},"content":{"rendered":"<p style=\"text-align: center;\"><iframe loading=\"lazy\" title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/JgrMzvasrm8\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p><span style=\"font-weight: 400;\">In this video, Dr. Roger Seheult of MedCram explains regarding the Pfizer vaccine and what was known about its ability to prevent transmission of the SARS-CoV-2.\u00a0 It has been alluded to recently that Pfizer was not being truthful regarding the study it did. Dr. Seheult unravels that statement.<\/span><\/p>\n<h2>How to get Emergency Use Authorization<\/h2>\n<p><span style=\"font-weight: 400;\">To get EUA (emergency use authorization) for a vaccine, you only need to show you can block primary infection i.e. primary cases. For EUA, you do not need to show you can block transmission for secondary cases. When doing a trial to determine the amount of secondary cases and even hospitalization and death, it takes a lot more time, people and money to study this secondary end point. These studies may still be done, but don\u2019t need to be done before the product goes to market.\u00a0 An <\/span><a href=\"https:\/\/t.co\/NInSYrkjj1\"><span style=\"font-weight: 400;\">article<\/span><\/a><span style=\"font-weight: 400;\"> written in October 2020 describes this issue. This article was written before any vaccines had even received EUA. <\/span><\/p>\n<h2>What was Pfizer&#8217;s endpoint?<\/h2>\n<p><span style=\"font-weight: 400;\">Pfizer in their studies went after primary cases to reach their endpoint because trying to determine secondary endpoints would not only cost time and money but also people were dying in hospitals during this time. It was critical to try and get something that might prevent primary infection and prevent death down the road. Pfizer\u2019s study was well powered to get the primary endpoints they were looking for. They also were upfront in stating they were not looking to see the interruption of transmission (ie person to person spread) in the initial studies. None of the vaccines for COVID-19 that were being initially investigated had this as an end point. These types of studies can be done and normally are done in after market studies. <\/span><\/p>\n<h2>What did the FDA know?<\/h2>\n<p><span style=\"font-weight: 400;\">The FDA released a statement in December stating that Pfizer\u2019s vaccine may be effective in preventing COVID-19 in the primary individual. The statement did not say anything about the vaccine preventing death or transmission or even hospitalization. The FDA further stated that data was not available to make a determination about how long the vaccine would provide protections or whether there is evidence that the vaccine prevents transmission of SARS-CoV-2 from person to person.\u00a0<\/span><\/p>\n<h2>What happened after market release?<\/h2>\n<p><span style=\"font-weight: 400;\">After marketing, there were several studies done that looked at the effect of vaccination on household transmission of SARS-CoV-2.\u00a0 One such <\/span><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMc2107717\"><span style=\"font-weight: 400;\">study, <\/span><\/a><span style=\"font-weight: 400;\">published in the NEJM, showed that overall the likelihood of household transmission was 40-50% lower in households of index patients who had been vaccinated 21 or more days before testing positive than in households of unvaccinated index patients. Another <\/span><a href=\"https:\/\/www.science.org\/doi\/epdf\/10.1126\/science.abl4292\"><span style=\"font-weight: 400;\">article<\/span><\/a><span style=\"font-weight: 400;\"> again reiterates that vaccination reduces transmission of SARS-CoV-2.\u00a0 These studies were not funded by pharmaceutical companies.\u00a0<\/span><\/p>\n<h2>Why is all of this necessary?<\/h2>\n<p><span style=\"font-weight: 400;\">If the endpoints are so rare, then why do we even have to do the studies later or even get vaccinated? With COVID-19, even though the chance of death is 1%, and even though this is a small number, when it is applied to a large population as in the U.S. population of 350 million it can be seen that it will still affect a large number of persons. Furthermore with a hospitalization rate of\u00a0 3-4%, it is easy to see how the hospitals can easily be overrun even with such a small percentage.\u00a0\u00a0<\/span><\/p>\n<h2>What are crisis protocols?<\/h2>\n<p><span style=\"font-weight: 400;\">What many people don\u2019t realize is that when hospitals become overrun, then resources become limited, especially in the healthcare industry.\u00a0 When this happens, hospitals turn to crisis protocols. Crisis protocols essentially limit resources to persons who are more likely to survive based on a series of algorithms. Depending on where a person lives, they probably had crisis protocols implemented or almost implemented at their local hospitals and many people were not even aware it was happening.\u00a0 If a significant amount of people are not treated early to prevent hospitalization, it will overwhelm those resources and the institutions will have to institute crisis protocols.\u00a0 \u00a0MedCram is dedicated to trying to prevent that by educating individuals on how to be healthy and avoid hospitalization and\/or death from illnesses.\u00a0\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">LINKS \/ REFERENCES:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Effect of Covid-19 Vaccination on Transmission of Alpha and Delta Variants (NEJM) |<\/span><a href=\"https:\/\/www.youtube.com\/redirect?event=video_description&amp;redir_token=QUFFLUhqbnE3azFsekRBS0JMVjIyQlJpeWtSUllsUno3Z3xBQ3Jtc0trOGdNSlFVMTYycWZJdlgwWHNhaUJEMkZ0cmtwWi03b0dDVHNVSjJmNThoSExhWFlDbHRrTXFMV1VGNEN0SVphM1RTSlYxYjJnSEpfb2dDVlFrbEdidHFKaVVqOUU4NnRMYlZ3cGdtd1FkZE1YaFkzOA&amp;q=https%3A%2F%2Fwww.nejm.org%2Fdoi%2Ffull%2F10.1056%2Fnejmoa2116597%23article_references&amp;v=JgrMzvasrm8\"> <span style=\"font-weight: 400;\">https:\/\/www.nejm.org\/doi\/full\/10.1056&#8230;<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Effect of Vaccination on Household Transmission of SARS-CoV-2 in England (NEJM) |<\/span><a href=\"https:\/\/www.youtube.com\/redirect?event=video_description&amp;redir_token=QUFFLUhqazcwQ19jaG1Va2lISEZTZjhEN0FYZTVkOV96d3xBQ3Jtc0ttcWpSd1EyRU1aN2J1MnBBOGJYR2x6OU8xQXRTOEYwb0o5RklNc1g4V2FLTGNRX0dseTFPTF9pYWhrbmg3YUVlRXYtQmQ0blRDcUtkSXBHQ2tKaTlCTW95d3Q2SERpd0p5cmlLd2RSWnAyXzE5LTV5VQ&amp;q=https%3A%2F%2Fwww.nejm.org%2Fdoi%2Ffull%2F10.1056%2FNEJMc2107717&amp;v=JgrMzvasrm8\"> <span style=\"font-weight: 400;\">https:\/\/www.nejm.org\/doi\/full\/10.1056&#8230;<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Impact of BNT162b2 Vaccination and Isolation on SARS-CoV-2 Transmission in Israeli Households: An Observational Study (American Journal of Epidemiology) |<\/span><a href=\"https:\/\/www.youtube.com\/redirect?event=video_description&amp;redir_token=QUFFLUhqbUMyS0ZJeVZ5YzlRNU1ocnVXUkE2elE1a0gzd3xBQ3Jtc0tsRGFlbHhfNGpOaUYxTzRISDhLVmZObWxCM05sM1c3RnpVbFJlQzZRa0RTLW9GUHVvOFpQQUNSVTVrOUZDMW5MaVJ0VTFRSmhBaTlYWkljQjZJMGJOUXRtRlI2cE0ycEU4Znc5NUs3a2t1TURyV0YyOA&amp;q=https%3A%2F%2Facademic.oup.com%2Faje%2Farticle%2F191%2F7%2F1224%2F6541606&amp;v=JgrMzvasrm8\"> <span style=\"font-weight: 400;\">https:\/\/academic.oup.com\/aje\/article\/&#8230;<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Vaccination with BNT162b2 reduces transmission of SARS-CoV-2 to household contacts in Israel (Science) |<\/span><a href=\"https:\/\/www.youtube.com\/redirect?event=video_description&amp;redir_token=QUFFLUhqbkhZa25LYTBzeVRYQTBlaG1WX2FLV3NHZXQzUXxBQ3Jtc0ttTXRNZERoSUNCUzZySVZLSWVLTWppaGFVZ0RGVnp4X0hNVmlCNjNtRFNVbkNWVUVuVUxFaG81SHMwSktGY1dOSVlHQlB4VHRyTU1DZnlWMmJLb3F2cF9KYnYwR3QtMmd6MC1fb1N1eUlCRGw0VzlKdw&amp;q=https%3A%2F%2Fwww.science.org%2Fdoi%2Fepdf%2F10.1126%2Fscience.abl4292&amp;v=JgrMzvasrm8\"> <span style=\"font-weight: 400;\">https:\/\/www.science.org\/doi\/epdf\/10.1&#8230;<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">The indirect effect of mRNA-based COVID-19 vaccination on healthcare workers\u2019 unvaccinated household members (Nature) |<\/span><a href=\"https:\/\/www.youtube.com\/redirect?event=video_description&amp;redir_token=QUFFLUhqbklwVkhRVmhwcjFNTDBIWDZEVUhLX2I2Nml6UXxBQ3Jtc0tsY240cDNuVmVLbHA4RC1qNXRwekl5YkdyQVJFaXJPSUU5emRQUDVpc0tIdWhXN0ZvTWdnNE5LcUNMOGJsS2wwVnNxQzVPSHR1a1N6bFRHQUlSNXRIVFBfSExWS1BacWY1djVYWW1vcE1PY2NnUnJVUQ&amp;q=https%3A%2F%2Fwww.nature.com%2Farticles%2Fs41467-022-28825-4&amp;v=JgrMzvasrm8\"> <span style=\"font-weight: 400;\">https:\/\/www.nature.com\/articles\/s4146&#8230;<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Will covid-19 vaccines save lives? Current trials aren\u2019t designed to tell us (BMJ) |<\/span><a href=\"https:\/\/www.youtube.com\/redirect?event=video_description&amp;redir_token=QUFFLUhqa3pZTVlJUlRRWVl2ZmhiQ21DZ3MxaGpJRHp2UXxBQ3Jtc0tueWVpdk9PMlNrOW9hamZpZTJZQzlhVzdacVFJLXpwOXk5amFPZ1ptMjE2VVYtcDhGOXg0cVhUemdNa1pVWFlGMDMtX0dDSTh1QkZISDNaTHhBN0J1NENodEEwRFI2V1M1c04xc0RyUjhJcFo3a2NqQQ&amp;q=https%3A%2F%2Ft.co%2FNInSYrkjj1&amp;v=JgrMzvasrm8\"> <span style=\"font-weight: 400;\">https:\/\/t.co\/NInSYrkjj1<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Pfizer exec laughs when asked whether they knew their product stopped transmission prior to release (Real Rukshan) |<\/span><a href=\"https:\/\/www.youtube.com\/watch?v=2YagXbprzFE&amp;t=0s\"> <span style=\"font-weight: 400;\">https:\/\/youtu.be\/2YagXbprzFE<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">FDA Takes Key Action in Fight Against COVID-19 By Issuing Emergency Use Authorization for First COVID-19 Vaccine (FDA) |<\/span><a href=\"https:\/\/www.youtube.com\/redirect?event=video_description&amp;redir_token=QUFFLUhqbkQwV0NSWnhfVmpsWG8xUDNRZjJXRko0cUtQQXxBQ3Jtc0ttendNSXpOYzJ3RkxZWFNqMFlHVlh2UXc0UGR5SEc4cFJxaGxYU2VpendwMkpWa0VteW9UZWhZOU9BYUIzYmFpTFo5S1Z2N1J0aUtNd25JTXRONDVUZVJTclRtajVfZ1piZWJneGdha1hHUnpXTVhsQQ&amp;q=https%3A%2F%2Fwww.fda.gov%2Fnews-events%2Fpress-announcements%2Ffda-takes-key-action-fight-against-covid-19-issuing-emergency-use-authorization-first-covid-19&amp;v=JgrMzvasrm8\"> <span style=\"font-weight: 400;\">https:\/\/www.fda.gov\/news-events\/press&#8230;<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Fast Facts on U.S. Hospitals, 2022 (AHA) |<\/span><a href=\"https:\/\/www.youtube.com\/redirect?event=video_description&amp;redir_token=QUFFLUhqbTBfRnJ3SXdxRzVNVGpFX0w2RjgtbUlNNUstQXxBQ3Jtc0ttSWJkdHNBc18yc2Uxc0RaLU5PYVMzemJjVHRTQTNvZVlwY1RWTnlWOXBNdGFLSExGVzJLYzBZZDU5R0FybGh4bXRGZ2xHVHJYUldSdC1iUkU5ZW1WZTRydHpCLVRRaEd6M2JEZWtYTFZTSkJjZlEwSQ&amp;q=https%3A%2F%2Fwww.aha.org%2Fstatistics%2Ffast-facts-us-hospitals&amp;v=JgrMzvasrm8\"> <span style=\"font-weight: 400;\">https:\/\/www.aha.org\/statistics\/fast-f&#8230;<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Coronavirus (COVID-19) Cases (Our World in Data) |<\/span><a href=\"https:\/\/www.youtube.com\/redirect?event=video_description&amp;redir_token=QUFFLUhqbkNOLU5YM0FRNll3U1pKZERxYzRuTU12d0M0Z3xBQ3Jtc0tsbjI4MG1sbVZLYUN1REttdXUteDJybHRlTmc2MVZXMU5Ddk53Q1dNa25kdTZsNmI4VW41VC0yVDdMRGJDWmdmSzlzdkhPSEV6VWFxdUtZVlFyZVVsdHVldUg2UWFRVms0SGhKWlVyZ3ppcGtVVzduUQ&amp;q=https%3A%2F%2Fourworldindata.org%2Fcovid-cases&amp;v=JgrMzvasrm8\"> <span style=\"font-weight: 400;\">https:\/\/ourworldindata.org\/covid-cases<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">\u201cI am frightened by what is coming\u201d: Texas hospitals could soon be overwhelmed by COVID-19 caseload, officials say (Texas Tribune) |<\/span><a href=\"https:\/\/www.youtube.com\/redirect?event=video_description&amp;redir_token=QUFFLUhqa0JkZnFaY1dlOHBmS3FLSUJiSDJfTkJ5X3lOZ3xBQ3Jtc0tuVHp1VWU3OER0WjNIYU9oOGxOc2dobWl6N09GY0NxQUw3SjhCaFpjX1ExejE2MVlfX2tKVldybzJWd3Q4cjBxVkh1WlQ2cDlWcFR6dGYyS21qRnRyX2xzTXpmTnJ3c1lOZDktdnh5NGljbHVtS1JiVQ&amp;q=https%3A%2F%2Fwww.texastribune.org%2F2021%2F08%2F10%2Ftexas-hospitals-crisis-covid%2F&amp;v=JgrMzvasrm8\"> <span style=\"font-weight: 400;\">https:\/\/www.texastribune.org\/2021\/08\/&#8230;<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Health Care Crisis Protocol for the State of Nebraska (DHHS) |<\/span><a href=\"https:\/\/www.youtube.com\/redirect?event=video_description&amp;redir_token=QUFFLUhqbDVmLTVpdV9sZi1oRU9Vb2RmY2NMTkdJRlhEZ3xBQ3Jtc0ttS1JJdmlOYkZuckU5NkhCY09KaWVPdzlOUUh4SkFmMjlyWlE5amFZVm5DRUpId242THM5UUctV2VaUVl6YUdpb0NydXl5MkktdXpEeTRqeWxhMkR3S0Z6dVA2Y0ZPMkFFT3NEQ0JCUUFOYjZBeXhnNA&amp;q=https%3A%2F%2Fdhhs.ne.gov%2FDocuments%2FNE-Crisis-Protocol.pdf&amp;v=JgrMzvasrm8\"> <span style=\"font-weight: 400;\">https:\/\/dhhs.ne.gov\/Documents\/NE-Cris&#8230;<\/span><\/a><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">All coronavirus updates are at MedCram.com (including more discussion on delta variant covid, COVID Delta, COVID children, natural immunity COVID 19, and more).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">MedCram Update 46:<\/span><a href=\"https:\/\/www.youtube.com\/watch?v=EFRwnhfWXxo&amp;t=0s\"> <span style=\"font-weight: 400;\">https:\/\/youtu.be\/EFRwnhfWXxo<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">MedCram Update 47:<\/span><a href=\"https:\/\/www.youtube.com\/watch?v=H1LHgyfPPQ8&amp;t=0s\"> <span style=\"font-weight: 400;\">https:\/\/youtu.be\/H1LHgyfPPQ8<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">MedCram Update 132:<\/span><a href=\"https:\/\/www.youtube.com\/watch?v=9OZZ6_M4OB0&amp;t=0s\"> <span style=\"font-weight: 400;\">https:\/\/youtu.be\/9OZZ6_M4OB0<\/span><\/a><\/p>\n<h2><b>Stay Tuned for More Updates\u00a0<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Our COVID-19 videos are always available for <\/span><i><span style=\"font-weight: 400;\">free <\/span><\/i><span style=\"font-weight: 400;\">(and ad-free) at<\/span><a href=\"https:\/\/www.medcram.com\/collections?category=covid-19-SARS-CoV-2\"> <span style=\"font-weight: 400;\">MedCram.com<\/span><\/a><span style=\"font-weight: 400;\">. In addition, check out our full library of courses and lectures on subjects ranging from<\/span> <a href=\"https:\/\/www.medcram.com\/courses\/hypertension-explained-clearly-2\"><span style=\"font-weight: 400;\">Hypertension Explained Clearly<\/span><\/a><span style=\"font-weight: 400;\"> to<\/span><a href=\"https:\/\/www.medcram.com\/courses\/sleep-apnea-explained-clearly\"> <span style=\"font-weight: 400;\">Sleep Apnea Explained Clearly<\/span><\/a><span style=\"font-weight: 400;\"> Course and many more!<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Meanwhile, you can find all of our COVID-19 videos compiled <\/span><a href=\"https:\/\/www.medcram.com\/collections?category=covid-19-SARS-CoV-2\"><span style=\"font-weight: 400;\">here<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Visit <\/span><a href=\"https:\/\/www.medcram.com\/\"><span style=\"font-weight: 400;\">MedCram.com<\/span><\/a><span style=\"font-weight: 400;\"> for updates on Monkeypox virus infectious disease and more.<\/span><\/p>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>In this video, Dr. Roger Seheult of MedCram explains regarding the Pfizer vaccine and what was known about its ability to prevent transmission of the SARS-CoV-2.\u00a0 It has been alluded to recently that Pfizer was not being truthful regarding the study it did. Dr. Seheult unravels that statement. How to get Emergency Use Authorization To&hellip;<!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":8,"featured_media":1362,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Does the Pfizer Vaccine Stop Transmission? - Medcram Blog<\/title>\n<meta name=\"description\" content=\"In this video, Dr. Roger Seheult of MedCram explains regarding the Pfizer vaccine and what was known about its ability to prevent transmission of the SARS-CoV-2.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.medcram.com\/covid-19\/pfizer-vaccine-ability-prevent-transmission-sars-cov-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Does the Pfizer Vaccine Stop Transmission? 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